Claudia Ferrioti
University of Bath, UK
Biography
Claudia Feriotti has her expertise in host-pathogens interactions and innate immunity, her current work is on the identification of molecules secreted by the intestinal epithelial cells which can control neutrophil transmigration from the intestinal lamina propria to the lumen in homeostatic environment or in the intestinal inflammatory diseases. She examines epithelial transcytosis mechanisms used by bacterial toxins for the delivery of biotherapeutics such as proteins, peptides, and siRNA. Her previous work was on the study of Klebsiella pneumonia-host interactions in human pulmonary infections. She analysed the Type I interferon function in the intracellular signalling pathways driven by Klebsiella infection in macrophages.
Abstract
Abstract : Trvp2 plays a critical role in hepoxilin A3-medited neutrophil transepithelial chemotaxis